Lizzo Responds To New 'South Park' Obesity Special Naming Her An Alternative To Ozempic

The newest South Park special, released on Friday, brutally clowned the celebrity Ozempic craze and even took aim at Lizzo as the "body positive" alternative to weight-loss drugs. And Lizzo was a surprisingly good sport about it.

In The End of Obesity, the women of South Park (and Randy Marsh) all become obsessed with injectable weight-loss medications, like Ozempic, Wegovy and Mounjaro. But without the help of insurance, the drugs are wildly expensive. So the poorer people of the town, like Eric Cartman and Sharon Marsh, are prescribed a much more affordable option: Lizzo.

An angry Cartman declares, "Rich people get Ozempic, poor people get body positivity!"

The special featured a spoof pharmaceutical ad for the "Lizzo" drug.

"FDA-approved Lizzo makes you feel good about your weight, and it costs 90% less than Ozempic," the voiceover declares. "In case studies, 70% of patients on Lizzo no longer care how much they weigh. Lizzo helps you eat everything you want and keep physical activity to a minimum.

"Are you living with concerns of obesity? Ask about the power of not giving a f-ck with Lizzo!"

Lizzo performs onstage during the opening night of The Special Tour in September 2022.

(Photo by Jason Koerner/Getty Images)

Posting to TikTok on Saturday night, Lizzo watched this scene with wide eyes and mouth agape. But, in the end, she seemed pretty unbothered. Kind of flattered, actually.

"I really showed the world how to love yourself and not give a f-ck to the point where these men in Colorado know who the f-ck I am and put it in their cartoon that’s been around for 25 years," she said. "I showed you all how to not give a f-ck, and I’m going to keep on showing you how to not give a f-ck."

Contrary to what the pop star says, you probably should give a f-ck about your health. But kudos to Lizzo for taking the jokes in stride — something we can't say about a certain Duchess of Sussex.

In addition to Lizzo and weight-loss-obsessed celebrities, South Park: The End of Obesity also mocks the confusing and disastrous state of the American healthcare system. The special is streaming now on Paramount+.