NFL Week 12 Opening Lines: Moneylines, Spreads, Totals For All 13 Games

Coming off of a spectacular Sunday of NFL action in Week 11, I'm already fired up to gamble on Week 12, even though the slate isn't as good. Luckily for me, sportsbooks release their opening spreads for next week's games during Sunday Night Football. And, if you want to make money on this racket, you must start prepping early. Or at least that's what professional sports bettors say. 

The marquee games of Week 12 are a battle for first in the NFC West between the Arizona Cardinals and Seattle Seahawks and the 2024 NFC divisional round rematch pitting the San Francisco 49ers against the Green Bay Packers. Six teams on a bye this week: Atlanta Falcons, Buffalo Bills, Cincinnati Bengals, New Orleans Saints, New York Jets, and Jacksonville Jaguars. 

NFL Week 12 Opening Lines 

The odds are courtesy of DraftKings as of 9:35 a.m. ET Monday, November 18. 

Thursday Night Football 

Pittsburgh Steelers (8-2) at Cleveland Browns (2-8)

• Moneyline (ML): Pittsburgh (-198) | Cleveland (+164)
• Spread: Steelers -4 (-105) | Browns +4 (-115)
• Total — 39 — Over (-112) | Under (-108)

1 p.m. ET window, Sunday (seven games) 

Dallas Cowboys (3-6)* at Washington Commanders (7-4) 

• ML: Dallas (+390) | Washington (-520)
• Spread: Cowboys +10 (-110) | Commanders -10 (-110)
• Total — 45 — Over (-110) | Under (-110)

*Dallas still needs to play the Houston Texans on Monday Night Football in NFL Week 12. 

Tampa Bay Buccaneers (4-6) at New York Giants (2-8) 

• ML: Tampa Bay (-238) | NYG (+195)
• Spread: Buccaneers -5 (-112) | Giants +5 (-108)
• Total — 41.5 — Over (-112) | Under (-108)

New England Patriots (3-8) at Miami Dolphins (4-6) 

• ML: New England (+300) | Miami (-380)
• Spread: Patriots +7.5 (-110) | Dolphins -7.5 (-110)
• Total — 45.5 — Over (-112) | Under (-108)

Detroit Lions QB Jared Goff passes the ball vs. the Jacksonville Jaguars at Ford Field. (Junfu Han/USA TODAY Network via Imagn Images)

Detroit Lions (9-1) at Indianapolis Colts (5-6) 

• ML: Detroit (-410) | Indianapolis (+320)
• Spread: Lions -8 (-110) | Colts +8 (-110)
• Total — 50.5 — Over (-110) | Under (-110)

Tennessee Titans (2-8) at Houston Texans (6-4)**

• ML: Tennessee (+295) | Houston (-375)
• Spread: Titans +7.5 (-110) | Texans -7.5 (-110)
• Total — 41.5 — Over (-110) | Under (-110)

**The Texans still need to play the Cowboys on Monday Night Football in NFL Week 12. 

Minnesota Vikings (8-2) at Chicago Bears (4-6) 

• ML: Minnesota (-180) | Chicago (+150)
• Spread: Vikings -3.5 (-110) | Bears +3.5 (-110)
• Total — 40 — Over (-108) | Under (-112)

Kansas City Chiefs (9-1) at Carolina Panthers (3-7)

• ML: Kansas City (-625) | Carolina (+455)
• Spread: Chiefs -11 (-108) | Panthers +11 (-112)
• Total — 41 — Over (-112) | Under (-108)

Kansas City Chiefs QB Patrick Mahomes drops back to pass against the Buffalo Bills at Highmark Stadium. (Gregory Fisher and Junfu Han-Imagn Images)

4 p.m. ET window, Sunday (three games) 

Denver Broncos (6-5) at Las Vegas Raiders (2-8) 

• ML: Denver (-245) | Las Vegas (+200)
• Spread: Broncos -5.5 (-112) | Raiders +5.5 (-108)
• Total — 41— Over (-108) | Under (-112)

San Francisco 49ers (5-5) at Green Bay Packers (7-3) 

• ML: San Francisco (+102) | Green Bay (-122)
• Spread: 49ers +1.5 (-110) | Packers -1.5 (-110)
• Total — 47.5— Over (-112) | Under (-108)

Arizona Cardinals (6-4) at Seattle Seahawks (5-5) 

• ML: Arizona (-108) | Seattle (-112)
• Spread: Cardinals +1 (-115) | Seahawks -1 (-105)
• Total — 48— Over (-108) | Under (-112)

Philadelphia Eagles RB Saquon Barkley runs past the Washington Commanders for a 39-yard touchdown at Lincoln Financial Field. (Eric Hartline-Imagn Images)

Sunday Night Football 

Philadelphia Eagles (8-2) at Los Angeles Rams (5-5) 

• ML: Philadelphia (-162) | LAR (+136)
• Spread: Eagles -3 (-105) | Rams +3 (-115)
• Total — 48 — Over (-108) | Under (-112)

Monday Night Football 

Baltimore Ravens (7-4) at Los Angeles Chargers (7-3)

• Houston: Baltimore (-130) | Los Angeles (+110)
• Spread: Ravens -2 (-112) | Chargers +2 (-108)
• Total — 47.5 — Over (-110) | Under (-110)

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